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cardiac-amyloidosis cardiac-amyloidosis

ATTR-cardiac amyloidosis
(ATTR-CM) is a serious,
progressive heart condition

Actor portrayals.

Symptoms
About ATTR-CM
Diagnosis and Management

ATTR-CM symptoms are often overlooked or misdiagnosed

Because the symptoms associated with ATTR-CM are shared with other heart conditions, a formal diagnosis can take years.

Symptoms may include:
  • Shortness of breath Shortness of breath
  • Swelling in legs or feet Swelling in legs
    or feet
  • Digestive problems Digestive problems
  • Tiredness or weakness Tiredness or weakness
  • Irregular heartbeat Irregular heartbeat
  • Nerve pain Nerve pain
Did you
know?
APPROXIMATELY
60%
of people diagnosed with ATTR-CM
experience carpal tunnel syndrome
info This is a common condition where nerves in the wrist become pinched, causing symptoms like numbness, tingling, and pain.
UP TO
40%
of people also experience spinal stenosis,
info Spinal stenosis is a condition where the space inside the spine narrows, which puts pressure on the spinal cord and nerves. Some people don’t have any symptoms, while others may experience pain, weakness, and numbness that worsens over time.
when the
space inside of the backbone is too small, causing
pain, tingling, numbness, and muscle weakness

Untreated ATTR-CM can stop you from living life the way you want

  • symptoms1
    Missing out on
    important life
    moments
  • symptoms1
    Having trouble
    with daily tasks
  • symptoms1
    Giving up
    activities you
    enjoy

Without intervention, issues become serious

  • symptoms1
    Heart failure
    info Heart failure means the heart isn’t pumping as well as it should. As a result, your body isn’t getting enough of the oxygen-rich blood it needs to work properly.
  • symptoms1
    More hospital
    visits
  • symptoms1
    Early death
Symptoms
About ATTR-CM
Diagnosis and Management
Next: About ATTR-CM

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Indication and Important Safety Information for Attruby

IMPORTANT SAFETY INFORMATION

Before taking Attruby, tell your healthcare provider about all your medical conditions, including if you:

  • are pregnant or plan to become pregnant

  • are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Attruby?
The most common side effects of Attruby were mild and include:

  • diarrhea

  • stomach-area (abdominal) pain

These are not all of the possible side effects of Attruby.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What is Attruby® (acoramidis)?

Attruby is a prescription medicine used to treat adults with a disease that affects the heart muscle called cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM), to reduce death and hospitalization related to heart problems.

It is not known if Attruby is safe and effective in children.

For the Full Prescribing Information and Patient Information for Attruby, visit Attruby.com/PI.