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Here you’ll find answers to the most frequently asked questions (FAQs) about Attruby

About Attruby

  • Attruby is a prescription medicine used to treat adults with a disease that affects the heart muscle called cardiomyopathy of wild-type info Wild-type refers to a form of ATTR-cardiac amyloidosis that people develop as they age. or variant transthyretin mediated amyloidosis (ATTR-CM), to reduce death and hospitalization related to heart problems. It is not known if Attruby is safe and effective in children.

  • Attruby is designed to stabilize the transthyretin (TTR) info Transthyretin, pronounced "trans-thy-retin," or TTR is an important protein that helps transport thyroxine, a thyroid hormone, and retinol (vitamin A) in your body. protein info Proteins are large molecules that are crucial for maintaining a healthy body. They play a role in virtually every bodily process, from building and repairing tissues to fueling your metabolism. in people with ATTR-cardiac amyloidosis. Over 90% of TTR proteins were stabilized with Attruby as seen in laboratory tests.

  • Ask your doctor about a serum TTR test, also known as a prealbumin info This test helps to measure overall health status. blood test. The results of the test will show how much stable TTR is present in your body and your doctor will be able to share what that means for you.

  • Take Attruby exactly as your healthcare provider tells you to. Take Attruby tablets by mouth 2 times a day, with or without food. Swallow tablets whole. Do not cut, crush, or chew tablets. To help you stay on track, download the Medisafe Digital Companion app to your smartphone for reminders and resources. Visit medisafe.com/download to get started.

  • Possible side effects may include diarrhea and abdominal pain. For most people, these side effects were mild and went away, so they could continue taking Attruby.

  • Store Attruby tablets at room temperature between 68–77 °F (20–25 °C). Store Attruby in the original blister card until use to protect from moisture.

Personal and financial support

  • ForgingBridges® offers personalized, one-on-one support for people prescribed Attruby and their care partners. They can help you navigate insurance, get financial support, and much more.

    Call 1-888-55-BRIDGE (1-888-552-7434),
    Mon-Fri, 8 AM to 8 PM ET, or visit ForgingBridges.com/Patient.

  • Advocacy groups can be a strong source of support, connecting you with resources and other families living with
    ATTR-CM. Please visit our Community page to learn more.

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Indication and Important Safety Information for Attruby

IMPORTANT SAFETY INFORMATION

Before taking Attruby, tell your healthcare provider about all your medical conditions, including if you:

  • are pregnant or plan to become pregnant

  • are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Attruby?
The most common side effects of Attruby were mild and include:

  • diarrhea

  • stomach-area (abdominal) pain

These are not all of the possible side effects of Attruby.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What is Attruby® (acoramidis)?

Attruby is a prescription medicine used to treat adults with a disease that affects the heart muscle called cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM), to reduce death and hospitalization related to heart problems.

It is not known if Attruby is safe and effective in children.

For the Full Prescribing Information and Patient Information for Attruby, visit Attruby.com/PI.