Proven results
with Attruby
Actor portrayals.
Attruby delivered rapid and sustained results in wild-type
and
hereditary
ATTR-cardiac amyloidosis (ATTR-CM)
In a 30-month clinical study,
people treated with Attruby did significantly better than those not taking Attruby
(placebo
). The results were based on a combined measure of survival and hospitalizations due to heart issues.
people treated with Attruby did significantly better than those not taking Attruby(placebo
). The results were based on a combined measure of survival and hospitalizations due to heart issues.
When comparing results in people treated with and without Attruby at 30 months,
people taking Attruby achieved:
On average, 0.3 vs 0.6 visits per year
3
months
Impact on survival and hospitalizations due to heart issues
Impact on health-related quality
of life
When comparing health-related quality of life measures in people treated with and without Attruby in a 30-month clinical study, people treated with Attruby reported better results:
-
Symptoms
Reduced shortness of breath and fatigue,
as well as less swelling in the legs, ankles, and feet. -
Physical abilities
Including the ability to walk 1 block on level ground or climb up a short flight
of stairs without stopping.‡ -
Social engagement
People were able to experience better overall enjoyment of life, such as visiting with family or friends.§
Impact on health-related quality of life was first observed after 3 months.*
*The treatment effect of Attruby on health
status was assessed using the Kansas City Cardiomyopathy Questionnaire-Overall Summary
(KCCQ-OS)
score composed of the physical limitation, symptom, social limitation, quality of life, and self-efficacy
domains, respectively.
†At the end of the 30-month study of adults with ATTR-CM, on average, people taking and not taking Attruby experienced a decline in their KCCQ-OS, a measure of health-related quality of life.
‡Other physical improvements included ability to do household chores and showering or bathing independently.
§This also included better engagement with their hobbies or enjoying intimate relationships.
*ATTR-cardiac amyloidosis is also known as transthyretin-mediated cardiomyopathy (ATTR-CM).
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